The change of glucose concentration by their interferents encountered in the glucose measurement is studied. We make the solutioins which are a aqueous glucose standards of 50, 150, 300mg/ dl, adding each hemoglobin, creatinine and bilirubin of
5,
10,
15, 20, 25, 30, 35mg/dl. We measure the glucose level with glucose oxidase, hexokinase, oxygen rate and dry chemistry methods. We compare the glucose level of aqueous glucose standards with that of their inferferents contatined glucose solutions.
In
this experimental study, the differences between glucose levels in the solution of standard glucose concentration of 50, 150, 300mg/dl adding creatinine, bilirubin and glucose levels in the solution of standard glucose concentration of 50, 150,
300mg/dl
no adding any interferents are considerably significant in all enzymatic methods and all interferents concentration(P<0.05 or P<0.01). In glucose measurement s of standard glucose solutions, oxygen rate method shows best sensitivity than other
methods,
dry chemistrry method shows poorest sensitivity than other methods. The sensitivity of glucose oxidase method is similar to that of hexokinase mothod. When measuring glucose solutions including interferents, bilirubin has more interfere action
than
creatinine, hemoglobin. Hemoglobin has less interfere action than other interferents. In this experimental study, all interferents made falsely low glucose levels in all enzymatic methods.
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